{"id":4436,"date":"2020-10-26T17:22:31","date_gmt":"2020-10-26T17:22:31","guid":{"rendered":"https:\/\/canue.ca\/?p=4436"},"modified":"2020-10-26T17:22:31","modified_gmt":"2020-10-26T17:22:31","slug":"october-26-2020","status":"publish","type":"post","link":"https:\/\/canue.ca\/fr\/october-26-2020\/","title":{"rendered":"October 26 | 2020"},"content":{"rendered":"<h3 class=\"heading-title\">Urban environment during early-life and blood pressure in young children.<\/h3>\n<div class=\"inline-authors\">\n<div class=\"authors\">\n<div class=\"authors-list\"><span class=\"authors-list-item \">Charline Warembourg,<\/span><span class=\"authors-list-item \">Mark Nieuwenhuijsen<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Ferran Ballester<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Montserrat de Castro<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Leda Chatzi<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Ana Esplugues<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Barbara Heude<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">L\u00e9a Maitre<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Rosemary McEachan<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Oliver Robinson<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">R\u00e9my Slama<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Jordi Sunyer<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Jose Urquiza<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">John Wright<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Xavier Basaga\u00f1a<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \">Martine Vrijheid.<\/span><\/div>\n<\/div>\n<\/div>\n<div><\/div>\n<div><strong>Environ Int. 2020 Oct 21;146:106174. doi: 10.1016\/j.envint.2020.106174.<\/strong><\/div>\n<div><\/div>\n<div>\n<p class=\"title\"><strong>Abstract<\/strong><\/p>\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<p><strong class=\"sub-title\"> Background: <\/strong> The urban environment is characterised by many exposures that may influence hypertension development from early life onwards, but there is no systematic evaluation of their impact on child blood pressure (BP).<\/p>\n<p><strong class=\"sub-title\"> Methods: <\/strong> Systolic and diastolic blood pressure were measured in 4,279 children aged 4-5 years from a multi-centre European cohort (France, Greece, Spain, and UK). Urban environment exposures were estimated during pregnancy and childhood, including air pollution, built environment, natural spaces, traffic, noise, meteorology, and socioeconomic deprivation index. Single- and multiple-exposure linear regression models and a cluster analysis were carried out.<\/p>\n<p><strong class=\"sub-title\"> Results: <\/strong> In multiple exposure models, higher child BP, in particular diastolic BP, was observed in association with higher exposure to air pollution, noise and ambient temperature during pregnancy, and with higher exposure to air pollution and higher building density during childhood (e.g., mean change [95% confidence interval] for an interquartile range increase in prenatal NO<sub>2<\/sub> = 0.7 mmHg[0.3;1.2]). Lower BP was observed in association with higher temperature and better street connectivity during childhood (e.g., temperature = -1.1[-1.6;-0.6]). Some of these associations were not robust in the sensitivity analyses. Mother-child pairs were grouped into six urban environment exposure clusters. Compared to the cluster representing the least harmful urban environment, the two clusters representing the most harmful environment (high in air pollution, traffic, noise, and low in green space) were both associated with higher diastolic BP (1.3[0.1;2.6] and 1.5[0.5;2.5]).<\/p>\n<p><strong class=\"sub-title\"> Conclusion: <\/strong> This first large systematic study suggests that living in a harmful urban environment may impact BP regulation in children. These findings reinforce the importance of designing cities that promote healthy environments to reduce long-term risk of hypertension and other cardiovascular diseases.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Urban environment during early-life and blood pressure in young children.<br \/>\nCharline Warembourg,Mark Nieuwenhuijsen,\u00a0Ferran Ballester,\u00a0Montserrat de Castro,\u00a0Leda Chatzi,\u00a0Ana Esplugues,\u00a0Barbara Heude,\u00a0L\u00e9a Maitre,\u00a0Rosemary McEachan,\u00a0Oliver Robinson,\u00a0R\u00e9my Slama,\u00a0Jordi Sunyer,\u00a0Jose Urquiza,\u00a0John Wright,\u00a0Xavier Basaga\u00f1a,\u00a0Martine Vrijheid.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-4436","post","type-post","status-publish","format-standard","hentry","category-article-de-la-semaine"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/canue.ca\/fr\/wp-json\/wp\/v2\/posts\/4436","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/canue.ca\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/canue.ca\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/canue.ca\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/canue.ca\/fr\/wp-json\/wp\/v2\/comments?post=4436"}],"version-history":[{"count":0,"href":"https:\/\/canue.ca\/fr\/wp-json\/wp\/v2\/posts\/4436\/revisions"}],"wp:attachment":[{"href":"https:\/\/canue.ca\/fr\/wp-json\/wp\/v2\/media?parent=4436"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/canue.ca\/fr\/wp-json\/wp\/v2\/categories?post=4436"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/canue.ca\/fr\/wp-json\/wp\/v2\/tags?post=4436"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}